Spirulina functions as a highly effective natural antacid, offering comprehensive relief from gastric hyperacidity while promoting long-term gastrointestinal health. Unlike conventional antacids that merely neutralize stomach acid temporarily, Spirulina addresses the root causes of acidity through its alkalizing mineral content—notably magnesium, calcium, and potassium—and anti-inflammatory bioactives such as phycocyanin and gamma-linolenic acid (GLA) (Karkos et al., 2011). These compounds help reduce mucosal inflammation, modulate acid secretion, and protect the gastric epithelium from oxidative stress and ulcerative damage (Chen et al., 2005). Studies have demonstrated Spirulina's ability to regulate gastric pH, inhibit Helicobacter pylori, and enhance mucosal healing, making it useful in the management of reflux disorders and gastritis (Al-Dhabi, 2013). Chlorophyll, abundant in Spirulina, further supports gastric alkalinity and helps buffer the acidic environment of the stomach (Abdel-Daim et al., 2013). Unlike synthetic antacids that may interfere with nutrient absorption and gut microbiota, Spirulina provides biocompatible, multi-targeted protection with added nutritional value.

Spirulina stands out as a top-tier natural supplement for enhancing digestive function, thanks to its enzymatic stimulation, anti-inflammatory properties, and prebiotic effects. Rich in chlorophyll, phycocyanin, and bioavailable micronutrients, Spirulina improves intestinal mucosal health and promotes enzymatic activity required for nutrient assimilation (Khan et al., 2005). Its high content of easily digestible proteins and amino acids relieves the burden on the gastrointestinal tract compared to complex animal proteins (Belay, 2002). Furthermore, Spirulina has demonstrated prebiotic-like effects, encouraging the growth of beneficial gut microbiota such as Lactobacillus and Bifidobacterium, which are essential for maintaining gut integrity and immune tolerance (Chamorro-Cevallos et al., 2008). Anti-inflammatory compounds in Spirulina, notably phycocyanin and GLA, also help reduce intestinal inflammation and oxidative stress, making it particularly useful in conditions such as gastritis, IBD, and dysbiosis (Remirez et al., 2002; Park et al., 2018). Its natural alkalinity helps buffer stomach acidity, while enhancing bile flow and detoxification pathways through the liver-gut axis. With a comprehensive and well-documented effect on gut health, Spirulina is a superior supplement for restoring digestive balance and enhancing nutrient absorption.

Spirulina emerges as one of the most promising natural interventions for geriatric health, owing to its multi-targeted efficacy in combating age-associated diseases such as cardiovascular disorders, neurodegeneration, sarcopenia, and immune decline. Rich in high-quality proteins, bioavailable iron, B-complex vitamins, phycocyanin, and γ-linolenic acid (GLA), Spirulina addresses critical deficiencies common in the elderly, supporting muscle maintenance, energy metabolism, and red blood cell formation (Khan et al., 2005; Belay, 2002). Its potent antioxidant profile—featuring phycocyanin, β-carotene, and superoxide dismutase—mitigates oxidative stress and mitochondrial dysfunction, key drivers of neurodegenerative diseases such as Alzheimer’s and Parkinson’s (Mao et al., 2005; Torres-Duran et al., 2007). Spirulina also exerts anti-inflammatory effects by modulating cytokines like IL-6 and TNF-α, which are often elevated in chronic inflammatory conditions and frailty syndromes (Remirez et al., 2002). Moreover, it enhances innate immunity by promoting macrophage and natural killer (NK) cell activity, helping the elderly resist infections and recover faster (Hirahashi et al., 2002). Clinical studies have further demonstrated improvements in lipid profiles, blood glucose control, and cognitive performance in older adults following Spirulina supplementation. Taken together, Spirulina offers a systems-level approach to healthy aging, making it a best-in-class nutraceutical for geriatric care.