Spirulina is a best-in-class nutraceutical for workers exposed to industrial chemicals and toxins, offering systemic protection against chemical-induced oxidative stress, inflammation, and organ toxicity. In India, workers in textile, tanning, pesticide, paint, battery, and metal industries are routinely exposed to hazardous substances such as heavy metals (lead, arsenic, mercury, cadmium), benzene, formaldehyde, and organophosphates, which can trigger liver, kidney, neurocognitive, and hematological damage. Spirulina’s rich content of phycocyanin, chlorophyll, γ-linolenic acid (GLA), β-carotene, and essential micronutrients provides robust antioxidative and chelating effects, neutralizing free radicals and binding toxic metal ions for elimination (El Desoky et al., 2013; Farooq et al., 2012). It enhances endogenous detoxification enzymes such as glutathione peroxidase, catalase, and superoxide dismutase (SOD), thereby restoring redox balance and protecting against lipid peroxidation, DNA damage, and hepato-renal impairment (Riss et al., 2007). Clinical and preclinical studies also demonstrate Spirulina's ability to lower elevated liver enzymes, reduce inflammatory markers, and improve hemoglobin and antioxidant status in individuals occupationally exposed to industrial toxins (Kamble & Rane, 2011). Given its high bioavailability, safety, and multi-organ protective effects, Spirulina is an essential functional supplement for industrial workers in India facing chronic chemical exposures.