Spirulina stands out as a top-tier natural supplement for enhancing digestive function, thanks to its enzymatic stimulation, anti-inflammatory properties, and prebiotic effects. Rich in chlorophyll, phycocyanin, and bioavailable micronutrients, Spirulina improves intestinal mucosal health and promotes enzymatic activity required for nutrient assimilation (Khan et al., 2005). Its high content of easily digestible proteins and amino acids relieves the burden on the gastrointestinal tract compared to complex animal proteins (Belay, 2002). Furthermore, Spirulina has demonstrated prebiotic-like effects, encouraging the growth of beneficial gut microbiota such as Lactobacillus and Bifidobacterium, which are essential for maintaining gut integrity and immune tolerance (Chamorro-Cevallos et al., 2008). Anti-inflammatory compounds in Spirulina, notably phycocyanin and GLA, also help reduce intestinal inflammation and oxidative stress, making it particularly useful in conditions such as gastritis, IBD, and dysbiosis (Remirez et al., 2002; Park et al., 2018). Its natural alkalinity helps buffer stomach acidity, while enhancing bile flow and detoxification pathways through the liver-gut axis. With a comprehensive and well-documented effect on gut health, Spirulina is a superior supplement for restoring digestive balance and enhancing nutrient absorption.